Publications

1.       Miao J, Lan T, Guo H, Wang J, Zhang G, Wang Z, Yang P, Li H, Zhang C, Wang Y, Li XM, Miao M. Characterization of SHARPIN knockout Syrian hamsters developed using CRISPR/Cas9 system. Animal Model Exp Med. 2023 Oct;6(5):489-498. doi: 10.1002/ame2.12265. Epub 2022 Sep 12. PubMed PMID: 36097701; PubMed Central PMCID: PMC10614123.

2.       Mordue DG, Hale SJ, Dennis WE, Vuong CV, Li XM, Yang N, Wormser GP. Plasma Blood Levels of Tafenoquine following a Single Oral Dosage in BALBc Mice with Acute Babesia microti Infection That Resulted in Rapid Clearance of Microscopically Detectable Parasitemia. Pathogens. 2023 Aug 31;12(9). doi: 10.3390/pathogens12091113. PubMed PMID: 37764921; PubMed Central PMCID: PMC10534932.

3.       Srivastava K, Cao M, Fidan O, Shi Y, Yang N, Nowak-Wegrzyn A, Miao M, Zhan J, Sampson HA, Li XM. Berberine-containing natural-medicine with boiled peanut-OIT induces sustained peanut-tolerance associated with distinct microbiota signature. Front Immunol. 2023;14:1174907. doi: 10.3389/fimmu.2023.1174907. eCollection 2023. PubMed PMID: 37575233; PubMed Central PMCID: PMC10415201.

4.       Wang J, Wood RA, Raymond S, Suárez-Fariñas M, Yang N, Sicherer SH, Sampson HA, Li XM. Double-Blind, Placebo-Controlled Study of E-B-FAHF-2 in Combination With Omalizumab-Facilitated Multiallergen Oral Immunotherapy. J Allergy Clin Immunol Pract. 2023 Jul;11(7):2208-2216.e1. doi: 10.1016/j.jaip.2023.03.051. Epub 2023 Apr 20. PubMed PMID: 37087097; PubMed Central PMCID: PMC10330343.

5.       Yang N, Maskey AR, Srivastava K, Kim M, Wang Z, Musa I, Shi Y, Gong Y, Fidan O, Wang J, Dunkin D, Chung D, Zhan J, Miao M, Sampson HA, Li XM. Inhibition of pathologic immunoglobulin E in food allergy by EBF-2 and active compound berberine associated with immunometabolism regulation. Front Immunol. 2023;14:1081121. doi: 10.3389/fimmu.2023.1081121. eCollection 2023. PubMed PMID: 36825019; PubMed Central PMCID: PMC9941740.

6.       Yang N, Musa I, Maskey AR, Li K, Wang Z, Liang B, Zhang S, Zhan J, Li XM. Formononetin isolated from Sophorae flavescentis inhibits B cell-IgE production by regulating ER-stress transcription factor XBP-1. Front Allergy. 2022;3:1056203. doi: 10.3389/falgy.2022.1056203. eCollection 2022. PubMed PMID: 36816476; PubMed Central PMCID: PMC9928687.

7.       Li K, Yu XH, Maskey AR, Musa I, Wang ZZ, Garcia V, Guo A, Yang N, Srivastava K, Dunkin D, Li JX, Guo L, Cheng YC, Yuan H, Tiwari R, Li XM. Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid. Front Pharmacol. 2022;13:1042756. doi: 10.3389/fphar.2022.1042756. eCollection 2022. PubMed PMID: 36793921; PubMed Central PMCID: PMC9922998.

8.       Cao M, Wang Y, Jing H, Wang Z, Meng Y, Geng Y, Miao M, Li XM. Development of an Oral Isoliquiritigenin Self-Nano-Emulsifying Drug Delivery System (ILQ-SNEDDS) for Effective Treatment of Eosinophilic Esophagitis Induced by Food Allergy. Pharmaceuticals (Basel). 2022 Dec 19;15(12). doi: 10.3390/ph15121587. PubMed PMID: 36559038; PubMed Central PMCID: PMC9784770.

9.       Maskey AR, Wang ZZ, Chen X, Dunkin D, Yang N, Soffer G, Yuan Q, Li XM. Computational analysis to define efficacy & molecular mechanisms of 7, 4'- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsies. Front Immunol. 2022;13:1015437. doi: 10.3389/fimmu.2022.1015437. eCollection 2022. PubMed PMID: 36591238; PubMed Central PMCID: PMC9797535.

10.   Fan X, McKnight T, Neshiwat J, Park S, Chung D, Li XM. Successful management of chronic urticaria and food allergies in a pediatric population using integrative traditional Chinese medicine therapy: a case series. Clin Mol Allergy. 2022 Nov 25;20(1):12. doi: 10.1186/s12948-022-00175-y. PubMed PMID: 36434719; PubMed Central PMCID: PMC9700962.

11.   Maskey A, Srivastava K, Soffer G, Dunkin D, Yuan Q, Li XM. Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible Mice. J Inflamm Res. 2022;15:5527-5540. doi: 10.2147/JIR.S372449. eCollection 2022. PubMed PMID: 36176352; PubMed Central PMCID: PMC9514888.

12.   Cao LH, He HJ, Zhao YY, Wang ZZ, Jia XY, Srivastava K, Miao MS, Li XM. Food Allergy-Induced Autism-Like Behavior is Associated with Gut Microbiota and Brain mTOR Signaling. J Asthma Allergy. 2022;15:645-664. doi: 10.2147/JAA.S348609. eCollection 2022. PubMed PMID: 35603013; PubMed Central PMCID: PMC9122063.

13.   Wang ZZ, Jia Y, Wang G, He H, Cao L, Shi Y, Miao M, Li XM. Dynamic covalent hydrogel of natural product baicalin with antibacterial activities. RSC Adv. 2022 Mar 15;12(14):8737-8742. doi: 10.1039/d1ra07553e. eCollection 2022 Mar 15. PubMed PMID: 35424809; PubMed Central PMCID: PMC8984956.

14.   Cao LH, Zhao YY, Bai M, Geliebter D, Geliebter J, Tiwari R, He HJ, Wang ZZ, Jia XY, Li J, Li XM, Miao MS. Mechanistic Studies of Gypenosides in Microglial State Transition and its Implications in Depression-Like Behaviors: Role of TLR4/MyD88/NF-κB Signaling. Front Pharmacol. 2022;13:838261. doi: 10.3389/fphar.2022.838261. eCollection 2022. PubMed PMID: 35370734; PubMed Central PMCID: PMC8973912.

15.   Liu C, Cao M, Yang N, Reid-Adam J, Tversky J, Zhan J, Li XM. Time-dependent dual beneficial modulation of interferon-γ, interleukin 5, and Treg cytokines in asthma patient peripheral blood mononuclear cells by ganoderic acid B. Phytother Res. 2022 Mar;36(3):1231-1240. doi: 10.1002/ptr.7266. Epub 2022 Feb 3. PubMed PMID: 35112740.

16.   Cao M, Liu C, Srivastava KD, Lin A, Lazarski C, Wang L, Maskey A, Song Y, Chen X, Yang N, Zambrano L, Bushko R, Nowak-Wegrzyn A, Cox A, Liu Z, Huang W, Dunkin D, Miao M, Li XM. Anti-IgE effect of small-molecule-compound arctigenin on food allergy in association with a distinct transcriptome profile. Clin Exp Allergy. 2022 Feb;52(2):250-264. doi: 10.1111/cea.14048. Epub 2021 Dec 28. PubMed PMID: 34757674.

17.   Shi Y, Chao L, Mei L, Chen Z, Li X, Miao M. Soluble tetraaminophthalocyanines indium functionalized graphene platforms for rapid and ultra-sensitive determination of rutin in Tartary buckwheat tea. Food Control. 2022 February; 132. doi: 10.1016/j.foodcont.2021.108550.

18.   Song Y, Wang ZZ, Wang L, Faybusovich P, Srivastava K, Liu C, Tversky J, Dunkin D, Busse P, Ren X, Miller R, Miao M, Li XM. Sophora flavescens Alkaloids and Corticosteroid Synergistically Augment IL-10/IL-5 Ratio with Foxp3-Gene-Epigenetic Modification in Asthma PBMCs. J Asthma Allergy. 2021;14:1559-1571. doi: 10.2147/JAA.S321616. eCollection 2021. PubMed PMID: 34992384; PubMed Central PMCID: PMC8711843.

19.   Chen X, Lai J, Song Y, Yang N, Gnjatic S, Gillespie V, Hahn W, Chefitz E, Pittman N, Jossen J, Benkov K, Dubinsky M, Li XM, Dunkin D. Butanol Purified Food Allergy Herbal Formula-2 Has an Immunomodulating Effect ex-vivo in Pediatric Crohn's Disease Subjects. Front Med (Lausanne). 2021;8:782859. doi: 10.3389/fmed.2021.782859. eCollection 2021. PubMed PMID: 34926527; PubMed Central PMCID: PMC8672768.

20.   He H, Cao L, Wang Z, Wang Z, Miao J, Li XM, Miao M. Sinomenine Relieves Airway Remodeling By Inhibiting Epithelial-Mesenchymal Transition Through Downregulating TGF-β1 and Smad3 Expression In Vitro and In Vivo. Front Immunol. 2021;12:736479. doi: 10.3389/fimmu.2021.736479. eCollection 2021. PubMed PMID: 34804018; PubMed Central PMCID: PMC8602849.

21.   Uzun S, Wang Z, McKnight TA, Ehrlich P, Thanik E, Nowak-Wegrzyn A, Yang N, Li XM. Improvement of skin lesions in corticosteroid withdrawal-associated severe eczema by multicomponent traditional Chinese medicine therapy. Allergy Asthma Clin Immunol. 2021 Jul 9;17(1):68. doi: 10.1186/s13223-021-00555-0. PubMed PMID: 34243796; PubMed Central PMCID: PMC8268267.

22.   Wang Z, Wang ZZ, Geliebter J, Tiwari R, Li XM. Traditional Chinese medicine for food allergy and eczema. Ann Allergy Asthma Immunol. 2021 Jun;126(6):639-654. doi: 10.1016/j.anai.2020.12.002. Epub 2020 Dec 10. Review. PubMed PMID: 33310179; NIHMSID:NIHMS1674680.

23.   Wang ZZ, Jia Y, Srivastava KD, Huang W, Tiwari R, Nowak-Wegrzyn A, Geliebter J, Miao M, Li XM. Systems Pharmacology and In Silico Docking Analysis Uncover Association of CA2, PPARG, RXRA, and VDR with the Mechanisms Underlying the Shi Zhen Tea Formula Effect on Eczema. Evid Based Complement Alternat Med. 2021;2021:8406127. doi: 10.1155/2021/8406127. eCollection 2021. PubMed PMID: 34055023; PubMed Central PMCID: PMC8143894.

24.   Wang ZZ, Li K, Maskey AR, Huang W, Toutov AA, Yang N, Srivastava K, Geliebter J, Tiwari R, Miao M, Li XM. A small molecule compound berberine as an orally active therapeutic candidate against COVID-19 and SARS: A computational and mechanistic study. FASEB J. 2021 Apr;35(4):e21360. doi: 10.1096/fj.202001792R. PubMed PMID: 33749932; PubMed Central PMCID: PMC8250068.

25.   Zhang Z, Li XM, Li Z, Lin H. Investigation of glycated shrimp tropomyosin as a hypoallergen for potential immunotherapy. Food Funct. 2021 Mar 21;12(6):2750-2759. doi: 10.1039/d0fo03039b. Epub 2021 Mar 8. PubMed PMID: 33683237.

26.   Shi Y, Zhang X, Mei L, Hu K, Chao L, Li X, Miao M. 2D Accordion‐like MXene Nanosheets as a Sensitive Electrode Material for Baicalin Sensing. Electroanalysis. 2021 January.

27.   Soffer G, Kaman K, Li XM. Successful Management of Eosinophilic Esophagitis Using Traditional Chinese Medicine: A Case Report. Yale J Biol Med. 2020 Dec;93(5):685-688. eCollection 2020 Dec. PubMed PMID: 33380930; PubMed Central PMCID: PMC7757072.

28.   Cao M, Zhan M, Wang Z, Wang Z, Li XM, Miao M. Development of an Orally Bioavailable Isoliquiritigenin Self-Nanoemulsifying Drug Delivery System to Effectively Treat Ovalbumin-Induced Asthma. Int J Nanomedicine. 2020;15:8945-8961. doi: 10.2147/IJN.S269982. eCollection 2020. PubMed PMID: 33223829; PubMed Central PMCID: PMC7671486.

29.   Shi Y, Zhang X, Mei L, Han D, Hu K, Chao L, Li X, Miao M. Sensitive acetaminophen electrochemical sensor with amplified signal strategy via non-covalent functionalization of soluble tetrahydroxyphthalocyanine and graphene. Microchemical Journal. 2020 October; 160:105608.

30.   Han DE, Shi Y, Tian P, Wei H, Miao M, Li XM. Development of an ultra-performance liquid chromatography-electrospray ionization-Orbitrap mass spectrometry method for determination of xanthopurpurin in rat plasma and its application to pharmacokinetic study. Biomed Chromatogr. 2020 Jul;34(7):e4838. doi: 10.1002/bmc.4838. Epub 2020 May 19. PubMed PMID: 32246852.

31.   Zhang Z, Li XM, Xiao H, Nowak-Wegrzyn A, Zhou P. IgE-binding epitope mapping of tropomyosin allergen (Exo m 1) from Exopalaemon modestus, the freshwater Siberian prawn. Food Chem. 2020 Mar 30;309:125603. doi: 10.1016/j.foodchem.2019.125603. Epub 2019 Oct 16. PubMed PMID: 31707198.

32.   Shi Y, Mei L, Zhang J, Hu K, Zhang X, Li Z, Miao M, Li X. Synthesis of Zinc Tetraaminophthalocyanine Functionalized Graphene Nanosheets as an Enhanced Material for Sensitive Electrochemical Determination of Uric Acid. Electroanalysis. 2020 March.

33.   Zhang Z, Li XM, Xiao H, Nowak-Wegrzyn A, Zhou P. Insight into the allergenicity of shrimp tropomyosin glycated by functional oligosaccharides containing advanced glycation end products. Food Chem. 2020 Jan 1;302:125348. doi: 10.1016/j.foodchem.2019.125348. Epub 2019 Aug 9. PubMed PMID: 31442704.

34.   Cao LH, Qiao JY, Huang HY, Fang XY, Zhang R, Miao MS, Li XM. PI3K-AKT Signaling Activation and Icariin: The Potential Effects on the Perimenopausal Depression-Like Rat Model. Molecules. 2019 Oct 15;24(20). doi: 10.3390/molecules24203700. PubMed PMID: 31618892; PubMed Central PMCID: PMC6832648.

35.   Tian S, Miao MS, Li XM, Bai M, Wu YY, Wei ZZ. Study on neuroendocrine-immune function of Phenylethanoid Glycosides of Desertliving Cistanche herb in perimenopausal rat model. J Ethnopharmacol. 2019 Jun 28;238:111884. doi: 10.1016/j.jep.2019.111884. Epub 2019 Apr 14. PubMed PMID: 30995546.

36.   Shi Y, Hu K, Cui Y, Cheng J, Zhao W, Li X. Magnetic triptycene-based covalent triazine frameworks for the efficient extraction of anthraquinones in slimming tea followed by UHPLC-FLD detection. Microchemical Journal. 2019 January; 146:525-533. doi: https://doi.org/10.1016/j.microc.2019.01.036.

37.   Zhou W, Chen Z, Li W, Wang Y, Li X, Yu H, Ran P, Liu Z. Systems pharmacology uncovers the mechanisms of anti-asthma herbal medicine intervention (ASHMI) for the prevention of asthma. Journal of functional foods. 2018 November; 52:611-619.

38.   Thanik E, Wisniewski JA, Nowak-Wegrzyn A, Sampson H, Li XM. Effect of traditional Chinese medicine on skin lesions and quality of life in patients with moderate to severe eczema. Ann Allergy Asthma Immunol. 2018 Jul;121(1):135-136. doi: 10.1016/j.anai.2018.03.004. Epub 2018 Mar 9. PubMed PMID: 29530759.

39.   Srivastava KD, Song Y, Yang N, Liu C, Goldberg IE, Nowak-Węgrzyn A, Sampson HA, Li XM. B-FAHF-2 plus oral immunotherapy (OIT) is safer and more effective than OIT alone in a murine model of concurrent peanut/tree nut allergy. Clin Exp Allergy. 2017 Aug;47(8):1038-1049. doi: 10.1111/cea.12936. Epub 2017 May 15. PubMed PMID: 28397379; PubMed Central PMCID: PMC5533629.

40.   Yang N, Srivastava K, Song Y, Liu C, Cho S, Chen Y, Li XM. Berberine as a chemical and pharmacokinetic marker of the butanol-extracted Food Allergy Herbal Formula-2. Int Immunopharmacol. 2017 Apr;45:120-127. doi: 10.1016/j.intimp.2017.01.009. Epub 2017 Feb 14. PubMed PMID: 28208101.

41.   Liu C, Yang N, Chen X, Tversky J, Zhan J, Chehade M, Miller RL, Li XM. The Flavonoid 7,4'-Dihydroxyflavone Prevents Dexamethasone Paradoxical Adverse Effect on Eotaxin Production by Human Fibroblasts. Phytother Res. 2017 Mar;31(3):449-458. doi: 10.1002/ptr.5767. Epub 2017 Jan 19. PubMed PMID: 28102022.

42.   Smith PK, Masilamani M, Li XM, Sampson HA. The false alarm hypothesis: Food allergy is associated with high dietary advanced glycation end-products and proglycating dietary sugars that mimic alarmins. J Allergy Clin Immunol. 2017 Feb;139(2):429-437. doi: 10.1016/j.jaci.2016.05.040. Epub 2016 Jul 15. Review. PubMed PMID: 27544741.

43.   Srivastava KD, Siefert A, Fahmy TM, Caplan MJ, Li XM, Sampson HA. Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy. J Allergy Clin Immunol. 2016 Aug;138(2):536-543.e4. doi: 10.1016/j.jaci.2016.01.047. Epub 2016 Apr 26. PubMed PMID: 27130858.

44.   Wang J, Jones SM, Pongracic JA, Song Y, Yang N, Sicherer SH, Makhija MM, Robison RG, Moshier E, Godbold J, Sampson HA, Li XM. Safety, clinical, and immunologic efficacy of a Chinese herbal medicine (Food Allergy Herbal Formula-2) for food allergy. J Allergy Clin Immunol. 2015 Oct;136(4):962-970.e1. doi: 10.1016/j.jaci.2015.04.029. Epub 2015 Jun 1. PubMed PMID: 26044855; PubMed Central PMCID: PMC4600418.

45.   Liu C, Yang N, Song Y, Wang L, Zi J, Zhang S, Dunkin D, Busse P, Weir D, Tversky J, Miller RL, Goldfarb J, Zhan J, Li XM. Ganoderic acid C1 isolated from the anti-asthma formula, ASHMI™ suppresses TNF-α production by mouse macrophages and peripheral blood mononuclear cells from asthma patients. Int Immunopharmacol. 2015 Aug;27(2):224-31. doi: 10.1016/j.intimp.2015.05.018. Epub 2015 May 21. PubMed PMID: 26004313; PubMed Central PMCID: PMC4635663.

46.   Liu C, Dunkin D, Lai J, Song Y, Ceballos C, Benkov K, Li XM. Anti-inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn's Disease Associated with Downregulation of NF-κB Signaling. Inflamm Bowel Dis. 2015 Aug;21(8):1918-25. doi: 10.1097/MIB.0000000000000439. PubMed PMID: 25993687; PubMed Central PMCID: PMC4509964.

47.   Chang LM, Song Y, Li XM, Sampson HA, Masilamani M. Dietary Elimination of Soybean Components Enhances Allergic Immune Response to Peanuts in BALB/c Mice. Int Arch Allergy Immunol. 2015;166(4):304-10. doi: 10.1159/000430497. Epub 2015 Jun 2. PubMed PMID: 26044955.

48.   Liu C, Weir D, Busse P, Yang N, Zhou Z, Emala C, Li XM. The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-κB, STAT6, and HDAC2. Phytother Res. 2015 Jun;29(6):925-32. doi: 10.1002/ptr.5334. Epub 2015 Mar 23. PubMed PMID: 25809288; PubMed Central PMCID: PMC4706450.

49.   Song Y, Wang J, Leung N, Wang LX, Lisann L, Sicherer SH, Scurlock AM, Pesek R, Perry TT, Jones SM, Li XM. Correlations between basophil activation, allergen-specific IgE with outcome and severity of oral food challenges. Ann Allergy Asthma Immunol. 2015 Apr;114(4):319-26. doi: 10.1016/j.anai.2015.01.006. PubMed PMID: 25841330.

50.   Zhou Z, Gong S, Li XM, Yang Y, Guan R, Zhou S, Yao S, Xie Y, Ou Z, Zhao J, Liu Z. Expression of Helicobacter pylori urease B on the surface of Bacillus subtilis spores. J Med Microbiol. 2015 Jan;64(Pt 1):104-110. doi: 10.1099/jmm.0.076430-0. Epub 2014 Oct 29. PubMed PMID: 25355934.